CMA Med Spa - Center for Modern Aesthetic Medicine

Downtown: 9050 Cypress Green Dr, Jacksonville, FL 32256

Jax Beach: 465 3rd Street North, Jacksonville Beach, FL 32250

CMA Medicine is a trusted Jacksonville med spa known for natural, confidence-boosting results. With locations in San Marco and Jax Beach, their expert team specializes in Botox, fillers, lasers, and personalized treatment plans that enhance your features without overdoing it. A clean, modern space and highly trained providers make every visit feel comfortable, customized, and results-driven.

Learn More

Coastal Health & Medical Spa 

Southside: 9050 Cypress Green Dr, Jacksonville, FL 32256

Coastal Health & Medical Spa in Jacksonville offers a welcoming, modern space where expert practitioners combine aesthetic treatments like Botox, fillers, and microneedling with medical-wellness services. Their focus is on tailored care and helping you look and feel your best — quick, quality results, no fluff. 

Learn More

Rejuvenate with Luxe Med Spa

Ponte Vedra: 330 A1A N, Suite 306, Ponte Vedra Beach, FL 32082

Luxe Renewal Wellness Spa is a family-owned practice in Ponte Vedra Beach, known for its warm, personal approach to aesthetic and wellness care. Along with refined Botox and injectable treatments, they specialize in supportive, results-driven medical weight-loss programs designed to help clients feel healthier and more confident. Their team makes every visit feel welcoming and individualized—combining family values with modern, effective treatments.

Learn More

B. Beautiful Aesthetics

Neptune Beach: 1300 Strand St., Suite A. Neptune Beach, FL 32266

B. Beautiful Aesthetics & Wellness is a boutique med-spa nestled in Neptune Beach, where founder Brie Peterson (APRN) brings over two decades of healthcare experience into the aesthetic realm. The mission is simple: through personalized and elegant treatments—from Botox and fillers to PRP, microneedling, and skin revitalization—clients are guided to feel confident in their best skin and best self.

Learn More

Jax Medi Spa

Southside: 3100 University Blvd S, Suite 100, Jacksonville, FL 32216 

Loved by locals for its welcoming atmosphere and reliable results, Jax Medi Spa offers Botox, fillers, facials, and more. Their providers prioritize education and comfort, making each visit feel relaxed, supportive, and tailored to your goals.

Learn More

Pure Hydration 

Riverside: 1650 Margaret St, Jacksonville, FL 32204

Jax Beach:  384 9th Ave N, Jacksonville, FL 32250

Pure Hydration is a refreshing wellness spot combining IV therapy with aesthetic options like Botox for a full-body pick-me-up. Pure Hydration is perfect for anyone who wants to look brighter, feel better, and leave with a healthy, renewed glow from the inside out.

Learn More

Thrive 

Town Center - 4888 Town Center Pkwy. Ste. 104, Jacksonville, FL 32246

Mobile IV Van

Bright, modern, and uplifting, Thrive helps clients achieve natural-looking rejuvenation without the overwhelm. Their Botox and skincare treatments are designed to enhance without overdoing—ideal for a clean, subtle “you but refreshed” look.

Learn More

Hello Smooth 

Bartram: 155 Bartram Market Dr, St Johns, FL 32259

Known for its upbeat vibe and approachable team, Hello Smooth makes aesthetic care feel easy and empowering. They’re especially loved for natural Botox results and a service style that feels friendly, genuine, and pressure-free.

Learn More

Elase Med Spa

Atlantic Beach: 42 East Coast Dr, Suite 201, Atlantic Beach, FL 32233

St. Johns: 3635 St Johns Ave, Jacksonville, Florida, 32205

Fernandina Beach: 961687 Gateway Blvd unit 101k, Fernandina Beach, Florida, 32034

Ponte Vedra: 115 Professional Dr suite 101, Ponte Vedra Beach, Florida, 32082

St. Augustine: 2100 A1A S suite 2, St. Augustine, Florida, 32080,

Town Center: 4853 Big Island Drive, Jacksonville, Florida, 32246

A polished, beautiful boutique spa where aesthetics and experience go hand in hand. Elease offers thoughtful, elevated Botox and skincare treatments in a calm, curated space that makes every visit feel special.

Learn More

PV Plastic Surgery

Ponte Vedra: 209 Ponte Vedra Park Dr, Ponte Vedra Beach, FL 32082

Nocatee: 480 Town Plaza Ave, Suite 150, Ponte Vedra, FL 32081

Annex: 220 Ponte Vedra Park Dr, Suite 140, Ponte Vedra Beach, FL 32082

St. Johns: 304 Ashourian Ave, Unit 107, St. Augustine, FL 32092

Fernandina: 5472 First Coast Hwy, #3, Fernandina Beach, FL 32034

Gate Parkway: 11512 Lake Mead Ave, #513, Jacksonville, FL 32256

A trusted destination led by board-certified experts. PV Plastic Surgery offers both surgical and non-surgical aesthetics, with Botox treatments known for their precision, safety, and naturally refined finish.

Learn More

Honorable Mentions

Concierge Cosmetics 

Ovme

One Dermatology

Eluma Laser & Aesthetics 

Modern Aesthetic Centers

Effect Med Spa

Balanced Soul Wellness

Beauty Theory 

Meridian Medical Spa

Premier Medical Spa

Ageless Rejuvenation Center

VIO Med Spa

Coastal Dermatology & Medspa

Bravada Studio

Be Beautiful Aesthetics 

Luxe Aesthetics

Beaches Dermatology

Avalii Aesthetics 

Reverie Aesthetics 

Beaches Facial Plastic Surgery 

Waves Aesthetics

Pure Harmony 

Contoura

Aesthetix Plus 

Ponte Vedra Vein Institute

BlueWater Wellness & Med Spa

Studio Lana

OBI BioAesthetic Institute

First Coast Mohs of Ponte Vedra

11 North Aesthetics

Medi Spa Amelia

London Medical Spa

Amelia Aesthetics & Wellness

Emjecting

Luminess Med Spa

Live Without Lines Med Spa

Facial Rejuvenation Centre

St Johns Aesthetics & Wellness

The Edge Aesthetics & Co.

One Med Spa

Youthful Medical Spa

Laser Loft

Rejuvenate MedSpa